Hey everyone!
SUCH a LONG time not writing here! Life has been very busy but I’ve been continuing to dose! I had quite a lot of reflux symptoms on a high dose of peanuts so I dropped gradually over time and found a happy level of 100mg daily. My body is definitely capable of tolerating more peanut than this however I find that that amount is just right with my busy life of working and being an adult! I also feel very comfortable and safe at this dose. No symptoms at all!
Anyway, I had my first set of blood work done after starting OIT and I will post the results below with a summary! I am so pleased and it shows that OIT absolutely works!
February 2023 PRE-OIT:
IgE peanut 3.81
AraH2 4.48
AraH6 4.31
AraH8 0.78
IGG <2.0
Immunoglobulin E 76
One Month into OIT:
IgE peanut 6.84
IGG 3.8
Immunoglobulin E 80
July 2025:
IgE peanut 1.81
AraH2 2.05
AraH6 1.79
AraH8 1.70
IGG 2.0
Immunoglobulin E 88
In SUMMARY:
✅ 1. Decrease in Peanut-specific IgE (from 6.84 → 1.81)
• This is a very positive trend and one of the major goals of OIT.
• It shows your immune system is gradually becoming less reactive to peanuts.
• IgE levels can rise early in OIT (which yours did), but typically drop with successful desensitization — as seen here.
✅ Ara h 2 & Ara h 6 Downtrending
• These are clinically important peanut components linked to more severe reactions.
• The drop from >4 to ~2 in both is very promising — a sign of reduced allergy risk.
⚠️ Ara h 8 Slight Increase
• Likely linked to birch pollen cross-reactivity, not considered dangerous in most cases.
• A rise in Ara h 8 is not typically a problem unless there are symptoms (e.g., oral itching from raw fruits/veggies).
✅ Peanut IgG Rising During OIT
• This is expected. IgG antibodies can act as blocking antibodies, helping reduce allergic reactions.
• A higher IgG during OIT is considered a marker of success.
OIT & Me 